Reviews for Techies

Life's Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis).

"What are my chances of developing COPD if one of my parents has the disease?" A systematic review and meta-analysis of prevalence of co-occurrence of COPD diagnosis in parents and offspring

The Path to Better Understanding Heart Failure Epidemiology.

Outcomes of Direct Oral Anticoagulants Co-Prescribed with Common Interacting Medications.

JOURNAL The American journal of cardiology DOI 10.1016/j.amjcard.2021.09.025 Author(s) D Sanborn;A Sugrue;M Amin;R Mehta;M Farwati;AJ Deshmukh;H Sridhar;A Ahmed;SJ Asirvatham;NN Ou;PA Noseworthy;AM Killu;SK Mulpuru;M Madhavan Abstract Direct oral anticoagulants (DOACs) can

Draft Article for Newsletter

TITLE Outcomes of Direct Oral Anticoagulants Co-Prescribed with Common Interacting Medications. JOURNAL The American journal of cardiology DOI 10.1016/j.amjcard.2021.09.025 Author(s) D Sanborn;A Sugrue;M Amin;R Mehta;M Farwati;AJ Deshmukh;H Sridhar;A Ahmed;SJ Asirvatham;NN Ou;PA Noseworthy;AM

Clinicopathological characteristics of IgG4-related lung disease.

JOURNAL BMC pulmonary medicine DOI 10.1186/s12890-021-01781-3 Author(s) J Liu;Y Liu;X Shen;Z He;T Yu;L Pang;X Jin;L Wang Abstract BACKGROUND Immunoglobulin G4-related lung disease (IgG4-RLD) is a rare entity. We retrospectively analyzed the clinical and histopathological characteristics of patients with pathologically confirmed

Quality of life and asthma control in pregnant women with asthma.

JOURNAL BMC pulmonary medicine DOI 10.1186/s12890-021-01797-9 Author(s) N Fazel;M Kundi;E Jensen-Jarolim;IM Pali-Schöll;A Kazemzadeh;H Esmaily;MF Abdizadeh;R Akbarzadeh;R Ahmadi;H Jabbari Abstract BACKGROUND Asthma is the most commonly occurring respiratory illness during pregnancy. Associations with complications of pregnancy and adverse perinatal

Chronic hypersensitivity pneumonitis is associated with an increased risk of venous thromboembolism: a retrospective cohort study.

JOURNAL BMC pulmonary medicine DOI 10.1186/s12890-021-01794-y Author(s) M Sobiecka;M Szturmowicz;K Lewandowska;A Kowalik;E Łyżwa;K Zimna;I Barańska;L Jakubowska;J Kuś;R Langfort;W Tomkowski Abstract BACKGROUND Idiopathic pulmonary fibrosis (IPF) and chronic hypersensitivity pneumonitis share commonalities in pathogenesis shifting haemostasis balance towards

Mathematical Modeling of Endemic Cholera Transmission.

JOURNAL The Journal of infectious diseases DOI 10.1093/infdis/jiab472 Author(s) DL Chao Abstract Mathematical modeling can be used to project the impact of mass vaccination on cholera transmission. Here, we discuss 2 examples for which indirect protection from mass vaccination needs to be considered. In the first,

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Cardiovascular morbidity in COPD: A study of the general population.

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Draft Article for Newsletter

TITLE "Big big renin*. Enzymatic and partial physical characterization of a new high molecular weight renin from normal human kidney. JOURNAL Circulation research DOI 10.1161/01.res.41.4.7 Author(s) JD Barrett;P Eggena;MP Sambhi Abstract https://fahad.focalize.md/big-big-renin-enzymatic-and-partial-physical-characterization-of-a-new-high-molecular-weight-renin-from-normal-human-kidney/ TITLE JNK2, a Newly-Identified SERCA2

Frequent Undetected Ward-Based Methicillin-Resistant Staphylococcus aureus Transmission Linked to Patient Sharing Between Hospitals.

JOURNAL Clinical infectious diseases : an official publication of the Infectious Diseases Society of America DOI 10.1093/cid/cix901 Author(s) O Tosas Auguet;RA Stabler;J Betley;MD Preston;M Dhaliwal;M Gaunt;A Ioannou;N Desai;T Karadag;R Batra;JA Otter;H Marbach;TG Clark;JD Edgeworth

Draft Article for Newsletter

TITLE Oral Immunotherapy With Human Secretory Immunoglobulin A Improves Survival in the Hamster Model of Clostridioides difficile Infection. JOURNAL The Journal of infectious diseases DOI 10.1093/infdis/jiab087 Author(s) EF Chiari;W Weiss;MR Simon;ST Kiessig;M Pulse;SC Brown;HR Gerding;M Mandago;K Gisch;C

Elevated oxidative stress and reciprocal reduction of vascular endothelial growth factor levels with severity of COPD.

JOURNAL Chest DOI 10.1378/chest.128.5.3191 Author(s) Kanazawa|Hiroshi|H|;Yoshikawa|Junichi|J| Abstract STUDY OBJECTIVES The prevalent theory concerning the pathogenesis of COPD is that it is an imbalance between oxidants and antioxidants. However, it has been reported that a decrease in vascular endothelial growth

The Mosaic mtr Locus as Major Genetic Determinant of Azithromycin Resistance of Neisseria gonorrhoeae-Germany, 2018.

JOURNAL The Journal of infectious diseases DOI 10.1093/infdis/jiab091 Author(s) S Banhart;R Selb;S Oehlmann;J Bender;S Buder;K Jansen;D Heuer Abstract Within the German Gonococcal Resistance Network's (GORENET) Neisseria gonorrhoeae (NG) sample collection, azithromycin-resistant NG isolates increased from 4.3% in 2016 to

Oral Immunotherapy With Human Secretory Immunoglobulin A Improves Survival in the Hamster Model of Clostridioides difficile Infection.

JOURNAL The Journal of infectious diseases DOI 10.1093/infdis/jiab087 Author(s) EF Chiari;W Weiss;MR Simon;ST Kiessig;M Pulse;SC Brown;HR Gerding;M Mandago;K Gisch;C von Eichel-Streiber Abstract Coadministration of human secretory IgA (sIgA) together with subtherapeutic vancomycin enhanced survival in the Clostridioides

JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship.

JOURNAL Circulation research DOI 10.1161/CIRCRESAHA.120.318409 Author(s) J Yan;DJ Bare;J DeSantiago;W Zhao;Y Mei;Z Chen;K Ginsburg;RJ Solaro;BM Wolska;DM Bers;SRW Chen;X Ai Abstract RATIONALE We recently discovered pivotal contributions of stress kinase JNK2 (c-Jun N-terminal kinase isoform

"Big big renin*. Enzymatic and partial physical characterization of a new high molecular weight renin from normal human kidney.

JOURNAL Circulation research DOI 10.1161/01.res.41.4.7 Author(s) JD Barrett;P Eggena;MP Sambhi Abstract

Effect of beta-blocking agents and angiotensin II on isoproterenol-stimulated renin release from rat kidney slices.

JOURNAL Circulation research DOI Author(s) AM Capponi;M Gourjon;MB Vallotton Abstract UNLABELLED Mechanisms by which beta-blocking agents decrease blood pressure and suppress renin release are incompletely understood. We previously demonstrated that renin release by kidney slices may be increased by beta-adrenergic agonists, and the present communication contains our

Evidence for a physiological role of renal sympathetic nerves in adrenergic stimulation of renin release in the rat.

JOURNAL Circulation research DOI Author(s) W Aoi;DP Henry;MH Weinberger Abstract Previous studies on renin release by an in vitro system of rat kidney slices, which is devoid of hemodynamic influences, have provided evidence that renin release is stimulated by a beta-adrenergic mechanism. We used this system to

Partial purification of a high molecular weight renin from hog kidney.

JOURNAL Circulation research DOI 10.1161/01.res.38.6.90 Author(s) M Levine;KE Lentz;JR Kahn;FE Dorer;LT Skeggs Abstract Previous investigators have reported finding a high molecular weight (HMW) renin in various species which is activated by acidification. Two laboratories have reported that a decrease

Metabolic and Molecular Imaging of the Diabetic Cardiomyopathy.

JOURNAL Circulation research DOI 10.1161/CIRCRESAHA.120.315899 Author(s) LR Peterson;RJ Gropler Abstract The term diabetic cardiomyopathy is defined as the presence of abnormalities in myocardial structure and function that occur in the absence of, or in addition to, well-established cardiovascular risk factors. A key contributor to

Type 2 Diabetes and Hypertension.

JOURNAL Circulation research DOI 10.1161/CIRCRESAHA.118.314487 Author(s) D Sun;T Zhou;Y Heianza;X Li;M Fan;VA Fonseca;L Qi Abstract RATIONALE In observational studies, type 2 diabetes mellitus (T2D) has been associated with an increased risk of hypertension, and vice versa; however, the causality